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Darifenacin HBr
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| D129992-5g | 133099-07-7 | 询价 |
| D129992-250mg | 133099-07-7 | 询价 |
| D129992-1g | 133099-07-7 | 询价 |
| D129992-50mg | 133099-07-7 | 询价 |
| D129992-10mg | 133099-07-7 | 询价 |
产品介绍
- 分子式 C28H30N2O2.HBr
- 分子量507.46
属性
| 熔点 | 228-230 °C |
| 敏感性 | 对湿度敏感 |
| 溶解性 | Soluble in water (<1 mg/ml at 25 °C), chloroform, DMSO (117 mg/ml at 25 °C), methanol, and ethanol (<1 mg/ml at 25 °C). |
| 存贮条件 | 储存温度 2-8°C |
描述
| 应用 | An M3 muscarinic acetylcholine receptor blocker. |
| 产品介绍 | Darifenacin HBr是一种选择性的M3 muscarinic（M3蕈毒碱）受体拮抗剂，pKi为8.9。 |
| 备注 | Darifenacin is a selective M3 muscarinic receptor antagonist with pKi of 8.9. |
| 生化机理 | Darifenacin hydrobromide is an antispasmodic muscarinic antagonist, selective for blocking the M3 muscarinic acetylcholine receptor, which is primarily responsible for bladder muscle contractions. Darifenacin hydrobromide has 9 and 12-fold greater affinity for M3 compared to M1 and M5, respectively, and 59-fold greater affinity for M3 compared to both M2 and M4. Darifenacin is used clinically to treat urinary incontinence and overactive bladder syndrome. |
| 别名 | 氢溴酸达非那新; {1-[2-(2,3-二氢苯并呋喃-5-基)乙基]-3-吡咯烷基}-2,2-二苯基乙酰胺氢溴酸盐;UK 88525-04;Enablex;Darifenacin hydrobromide;(3S)-1-[2-(2,3-Dihydro-5-benzofuranyl)ethyl]-α,α-diphenyl-3-pyrrolidineacetamide hydrobromide ;UK 88525-04;{1-[2-(2,3-Dihydrobenzofuran-5-yl)ethyl]-3-pyrrolidnyl}-2,2-diphenylacetamide hydrobromide;Diphenyl-acetamide hydrobromide |
Darifenacin HBr信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Darifenacin HBr报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途