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马来酸氯苯那敏
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| C129233-100g | 113-92-8 | 询价 |
| C129233-25g | 113-92-8 | 询价 |
| C129233-500g | 113-92-8 | 询价 |
| C129233-5g | 113-92-8 | 询价 |
产品介绍
- 分子式 C16H19ClN2.C4H4O4
- 分子量390.86
- Beilstein号
- EC号 204-037-5
- MDL号 MFCD00069225
- PubChem编号 24892764
属性
| 熔点 | 130-135° |
| 敏感性 | 对光敏感 |
| 溶解性 | Solubility: Soluble in water |
描述
| 应用 |
An antagonist of the histamine H1-receptor.(±)-Chlorpheniramine maleate salt has been used: · as H1 receptor antagonist to determine the receptor function · to block the effect of compound 48/80 on plasma IGF-I · as a standard for fast sensing and determination by sequential injector coupled with potentiometer |
| 产品介绍 | Chlorpheniramine Maleate是一种组胺H1受体拮抗剂，IC50为12 nM。 |
| 备注 | Chlorpheniramine (Chlorpheniramine maleate, Chlorphenamine) is an histamine H1 receptor antagonist with IC50 of 12 nM. |
| 生化机理 | Chlorpheniramine Maleate is a small molecule H1-receptor antagonist. Increased ornithine decarboxylase activity induced in an ischemia-reperfusion state was attenuated by Chlorpheniramine Maleate, indicating that this increase is mediated through engagement of the H1-receptor by histamine. Histamine-mediated repair of intestinal mucosa following ischemia-reperfusion was also demonstrated to operate through the H1-receptor with Chlorpheniramine Maleate. Induction of ornithine decarboxylase was blocked by Chlorpheniramine Maleate in Ehrlich carcinoma and MCF-7 cells. The positive inotropic effect of H1-receptor stimulation by histamine on protein tyrosine phosphorylation in guinea pig left atrium was antagonized by Chlorpheniramine Maleate. |
| 别名 | 马来酸氯苯那敏;扑尔敏;氯屈米通;马来那敏;Chlorphenamine maleate; Piriton;Puermin; Chlortrimeton |
马来酸氯苯那敏信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于马来酸氯苯那敏报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途