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Mizolastine

品牌 厂商性质 产地 货期
阿拉丁 生产商 上海 现货

询价
产品参数
货号 CAS号 操作
M129245-1g 108612-45-9 询价
M129245-200mg 108612-45-9 询价
M129245-5g 108612-45-9 询价
产品介绍

  • 分子式 C24H25FN6O
  • 分子量432.49
  • Beilstein号
  • EC号
  • MDL号
  • PubChem编号

属性

溶解性
  • DMSO <1 mg/mL
  • Water <1 mg/mL
  • Ethanol <1 mg/mL
  • 存贮条件 储存温度-20°C

    描述

    应用 Mizolastine是组胺H1受体拮抗剂,IC50为47 nM。
    产品介绍 Mizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions. Target: Histamine H1-receptor Mizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions. It does not prevent the actual release of histamine from mast cells, just prevents it binding to receptors. Side effects can include dry mouth and throat. Mizolastine has demonstrated antiallergic effects in animals and healthy volunteers and anti-inflammatory activity in animal models. Double-blind trials have shown mizolastine to be significantly more effective than placebo and as effective as other second generation antihistamine agents, such as loratadine or cetirizine, in the management of patients with perennial or seasonal allergic rhinitis and in patients with chronic idiopathic urticaria. Available data also suggest that prophylactic administration of mizolastine is significantly more effective than placebo and as effective as prophylactic terfenadine in delaying the onset of symptoms of seasonal allergic rhinitis.
    备注 Mizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions.
    别名 咪唑司汀;SL 850324

    Mizolastine信息由上海阿拉丁生化科技股份有限公司为您提供,如您想了解更多关于Mizolastine报价、型号、参数等信息,欢迎来电或留言咨询。

    注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途