诚信认证：
工商注册信息已核实！
IKK-16 (IKK Inhibitor VII)
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
| 货号 | CAS号 | 操作 |
|---|---|---|
| I129698-10mg | 873225-46-8 | 询价 |
| I129698-1mg | 873225-46-8 | 询价 |
| I129698-50mg | 873225-46-8 | 询价 |
- 分子式 C28H29N5OS
- 分子量483.63
属性
| 溶解性 |
|
| 存贮条件 | 储存温度-20°C |
描述
| 备注 | IKK 16 is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively. |
| 生化机理 |
Description： IC50 value: 40nM( forIKK-2);70nM(for Ikk complex);200nM(for Ikk-1) IKK 16 is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively. IKKs play an important role in the NF-KB signal pathway. In vitro: K IKK-16 inhibits TNFα-stimulated expression of the adhesion molecules E-selectin, ICAM-1, and VCAM-1 in HUVEC cells. Although IKK-16 shows activity in the IFNγ-induced expression of β2 microglobulin or HLA-DR, its potency in these assays is 4- to 10-fold weaker. 1]. In vivo: N/A Clinical trial: N/A |
| 别名 | Methanone, [4-[(4-benzo[b]thien-2-yl-2-pyrimidinyl)amino]phenyl][4-(1-pyrrolidinyl)-1-piperidinyl]-;Methanone, [4-[(4-benzo[b]thien-2-yl-2-pyrimidinyl)amino]phenyl][4-(1-pyrrolidinyl)-1-piperidinyl]- |
IKK-16 (IKK Inhibitor VII)信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于IKK-16 (IKK Inhibitor VII)报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途