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Ganciclovir
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| G129109-100g | 82410-32-0 | 询价 |
| G129109-1g | 82410-32-0 | 询价 |
| G129109-25g | 82410-32-0 | 询价 |
| G129109-5g | 82410-32-0 | 询价 |
| G129109-100g | 82410-32-0 | 询价 |
| G129109-1g | 82410-32-0 | 询价 |
| G129109-25g | 82410-32-0 | 询价 |
| G129109-5g | 82410-32-0 | 询价 |
产品介绍
- 分子式 C9H13N5O4
- 分子量255.23
- Beilstein号
- EC号
- MDL号 MFCD00870588
- PubChem编号 24278453
属性
| 熔点 | 250°C(dec.)(lit.) |
| 溶解性 | Soluble in 0.1 M HCl (10 mg/ml), DMSO (5 mg/ml), water (2 mg/ml), hot methanol, and ethanol (<1 mg/ml). |
| 存贮条件 | 储存温度 2-8°C |
描述
| 应用 | A nucleoside analog structurally related to Acyclovir. |
| 产品介绍 | Ganciclovir 是一种抗病毒药，作用于猫科动物1型疱疹病毒，IC50为5.2 μM。 |
| 备注 | Ganciclovir is an antiviral drug for feline herpesvirus type-1 with IC50 of 5.2 μM. |
| 生化机理 | Ganciclovir is a nucleoside analog structurally related to Acyclovir that acts as a prodrug activated by phosphorylation. Ganciclovir has been used in the study of “suicide” gene therapy in cancer research, where upon expression of a viral suicide gene encoding herpes simplex virus, thymidine kinase (TK), the non-toxic prodrug ganciclovir, is converted to an active phosphorylated analog that can be incorporated into the DNA of replicating eukaryotic cells, causing death of the malignant dividing cell. Causes an irreversible cell cycle arrest at the G2/M checkpoint. Ganciclovir has also been used to study the loss of telomeres and to evaluate sensitivity of viruses to antiviral agents. |
| 别名 | 更昔洛韦;9-(1,3-二羟基-2-丙氧甲基)鸟嘌呤;BW 759; 2'-Nor-2'-deoxyguanosine;2-Amino-1,9-dihydro-9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)-6H-purin-6-one; 9-((2-Hydroxy-1-(hydroxymethyl)ethoxy)-methyl)guanine; 9-(1,3-Dihydroxy-2-propoxymethyl)guanine; 2'-NDG; |
Ganciclovir信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Ganciclovir报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途