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AN-2728
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
阿拉丁 | 生产商 | 上海 | 现货 |
货号 | CAS号 | 操作 |
---|---|---|
A127102-100mg | 906673-24-3 | 询价 |
A127102-25mg | 906673-24-3 | 询价 |
A127102-5mg | 906673-24-3 | 询价 |
- 分子式 C14H10BNO3
- 分子量251.05
- Beilstein号
- EC号 MFCD17169940
- MDL号
- PubChem编号
属性
溶解性 | DMSO |
存贮条件 | 储存温度-20°C |
描述
生化机理 |
AN-2728 is a topically administered, boron-containing, anti-inflammatory compound that inhibits PDE4 activity and thereby suppresses the release of TNFalpha, IL-12, IL-23 and other cytokines. AN-2728 appears to have good therapeutic potential, although further and larger trials are required to assess the long-term safety and characterize the broad utility of this drug. AN-2728 shows potent activity both in vitro and in vivo. AN-2728 is now in clinical development for the topical treatment of psoriasis and being pursued for the topical treatment of atopic dermatitis. |
别名 | AN2728;AN 2728;4-((1,3-二氢-1-羟基-2,1-苯并氧杂硼杂环戊烷-5-基)氧基)苯甲腈;;AN2728;AN 2728; 4-((1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy)benzonitrile |
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途