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GAP-134
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
阿拉丁 | 生产商 | 上海 | 现货 |
货号 | CAS号 | 操作 |
---|---|---|
G126343-10mg | 943134-39-2 | 询价 |
G126343-50mg | 943134-39-2 | 询价 |
G126343-5mg | 943134-39-2 | 询价 |
- 分子式 C14H17N3O4
- 分子量291.3
属性
溶解性 | DMSO |
存贮条件 | 储存温度-20°C |
描述
生化机理 |
Gap junction uncoupling can alter conduction pathways and promote cardiac re-entry mechanisms that potentiate many supraventricular arrhythmias, such as atrial fibrillation (AF) and atrial flutter (AFL). GAP-134 (Danegaptide), a small modified dipeptide, has been identified as a potent and selective second generation gap junction modifier with oral bioavailability. Gap junction modifier GAP-134, showed consistent efficacy on measures of conduction and AF/AFL inducibility in the canine sterile pericarditis model. GAP-134 is a pharmalogical agent with a favorable clinical safety profile and potential antiarrhythmic efficacy, as already confirmed in phase I clinical trials. |
GAP-134信息由上海阿拉丁生化科技股份有限公司为您提供,如您想了解更多关于GAP-134报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途