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Fidaxomicin

品牌 厂商性质 产地 货期
阿拉丁 生产商 上海 现货

询价
产品参数
货号 CAS号 操作
F129607-50mg 873857-62-6 询价
F129607-100mg 873857-62-6 询价
F129607-250mg 873857-62-6 询价
F129607-5mg 873857-62-6 询价
产品介绍

  • 分子式 C52H74Cl2O18
  • 分子量1058.04

属性

溶解性
  • DMSO 100 mg/mL
  • Water <1 mg/mL
  • Ethanol 22 mg/mL
  • 存贮条件 储存温度-20°C

    描述

    应用 A macrocyclic antibiotic.
    产品介绍 Fidaxomicin 是一种窄谱的大环类抗生素,抑制RNA聚合酶σ亚基。
    备注 Fidaxomicin is a narrow spectrum macrocyclic antibiotic that inhibits RNA polymerase sigma subunit.
    生化机理 Fidaxomicin is a recently approved antibiotic with a confusing history dating back to its original isolation in 1975. Fidaxomicin is the major analogue of a family of macrocyclic lactones isolated independently by three different groups from cultures belonging to three different genera (Actinoplanes, Dactylosporangium and Micromonospora) known as lipiarmycin A3, tiacumicin B and clostomicin B1, respectively. Fidaxomicin is a narrow spectrum antibiotic with excellent activity against Gram positive bacteria, notably Clostridium difficile. Fidaxomicin acts in the gastrointestinal tract without undue disruption to gut microbial flora.
    别名 非达霉素;OPT-80, PAR-101;Oxacyclooctadeca-3,5,9,13,15-pentaen-2-one, 3-[[[6-deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-β-D-mannopyranosyl]oxy]methyl]-12-[[6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-β-D-lyxo-hexopyranosyl]oxy]-11-ethyl-8-hydroxy-

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    注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途