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Elaiophylin
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| E129956-1mg | 37318-06-2 | 询价 |
| E129956-5mg | 37318-06-2 | 询价 |
| E129956-10mg | 37318-06-2 | 询价 |
产品介绍
属性
| 溶解性 | Soluble in ethanol (5 mg/ml at 25 °C), methanol, DMF, DMSO (49 mg/ml at 25 °C), and water (<1 mg/ml at 25 °C). |
| 存贮条件 | 储存温度-20°C |
描述
| 应用 | A macrolide antibiotic with immunosuppresive activity. |
| 产品介绍 | Elaiophylin大环内脂类抗菌素，作用于恶性疟原虫K1a 和布氏布锥虫GUTat 3.1 品系，具有抗原生动物活性，IC50分别为370 ng/mL和460 ng/mL。 |
| 备注 | Elaiophylin shows antiprotozoal activity against Plasmodium falciparum K1a and Trypanosoma brucei brucei GUTat 3.1 strains with IC50 of 0.36 μM and 0.45 μM, respectively. |
| 生化机理 | Elaiophylin is a highly characteristic macrolide antibiotic that was first isolated from a culture of Streptomyces melanosporus. Elaiophylin demonstrates antifungal activity when combined with metabolite rapamycin. Elaiophylin shows shown cytotoxicity against mammalian tumor cells, protozoa, nematodes and antibacterial activity aganst gram-positive bacteria. The compound has also displayed immunosuppressive activity through inhibition of B-cell stimulation and inhibiting proliferation of lymphocytes stimulated by mitogens. Elaiophylin has been found to have antihelminthic to inhibit nitric oxide synthesis. Elaiophylin is an inhibitor of 5 α-Reductase and NOS. |
| 别名 | 洋橄榄叶素;Azalomycin-B; Gopalamicin; Salbomycin; |
Elaiophylin信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Elaiophylin报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途