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Dynasore
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| D125461-50mg | 304448-55-3 | 询底价 |
| D125461-10mg | 304448-55-3 | 询底价 |
| D125461-250mg | 304448-55-3 | 询底价 |
产品介绍
属性
| 溶解性 | Soluble in DMSO (100 mM), and ethanol (5 mM). Insoluble in water |
| 存贮条件 | 储存温度 2-8°C |
描述
| 应用 | An inhibitor of Dynamin I and Dynamin II |
| 产品介绍 | Dynasore是一种可渗透细胞的，可逆的，非竞争性的dynamin（发动蛋白）抑制剂，抑制dynamin 1/2的GTPase活性，IC50为15 μM，也抑制线粒体dynamin Drp1，对其他小GTP酶没有作用效果。 |
| 备注 | Dynasore is a cell-permeable, reversible non-competitive dynamininhibitor of GTPase activity of dynamin 1/2, with IC50 of 15 μM, also inhibits the mitochondrial dynamin Drp1, with no effect against other small GTPase. |
| 生化机理 | Dynasore is a non-competitive, cell-permeable semicarbazone compound inhibitor of Dynamin I and Dynamin II. Members of the Dynamin family, including Dynamin I, Dynamin II and Dynamin III, are GTPase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin I is localized to the central nervous system, while Dynamin II exhibits ubiquitous distribution with highest expression found in testis. Dynasore acts as a potent inhibitor of endocytic pathways known to depend on dynamin by blocking coated vesicle formation. Dynamin Inhibitor I, Dynasore is an inhibitor of DRP1. |
| 别名 | 3-羟基-2-萘甲酸[(3,4-二羟基苯基)亚甲基]酰肼;3-Hydroxy-2-naphthalenecarboxylic acid [(3,4-dihydroxyphenyl)methylene]hydrazide |
Dynasore信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Dynasore报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途