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其他小分子
Clotrimazole
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| C129965-5g | 23593-75-1 | 询价 |
| C129965-100g | 23593-75-1 | 询价 |
| C129965-250g | 23593-75-1 | 询价 |
| C129965-25g | 23593-75-1 | 询价 |
产品介绍
- 分子式 C22H17ClN2
- 分子量344.84
- EC号 245-764-8
- MDL号 MFCD00057220
- PubChem编号 24278327
属性
| 熔点 | 141-149° C |
| 溶解性 | Soluble in DMSO (25 mM), chloroform (50 mg/ml), DMF, ethyl acetate, ethanol, methanol, and acetone. |
描述
| 应用 | An antifungal compound and CYP inhibitor |
| 产品介绍 | Clotrimazole是一种合成的抗真菌药物，是imidazole的广谱衍生物 |
| 备注 | Clotrimazole is a synthetic, antifungal and broad-spectrum derivate of imidazole. |
| 生化机理 | Clotrimazole is an imidazole derivative and an antifungal compound and a CYP (cytochrome P450) inhibitor. Clotrimazole has been shown to block the intermediate-conductance, IK1 channels (Ca2+ activated K+ channels), in cells such as erythrocytes. In vitro studies of various yeast strains have demonstrated susceptibility to clotrimazole. Clotrimazole is an activator of MB67 and an inhibitor of CYP3A4 and CYP51A1. |
| 别名 | 1-[(2-氯苯基)二苯甲基]-1H-咪唑;三苯氯甲咪唑;氯苯甲咪唑;克霉唑;1-[(2-氯苯基)二苯甲基]咪唑;1-(2-氯三苯甲基)咪唑;1-[(2-Chlorophenyl)diphenylmethyl]-1H-imidazole;1-(o-Chlorotrityl)imidazole ;1-[(2-Chlorophenyl)diphenylmethyl]imidazole ;1-(2-Chlorotrityl)imidazole |
Clotrimazole信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Clotrimazole报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途