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卡巴他赛
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
| 货号 | CAS号 | 操作 |
|---|---|---|
| C125379-100mg | 183133-96-2 | 询底价 |
| C125379-250mg | 183133-96-2 | 询底价 |
| C125379-500mg | 183133-96-2 | 询底价 |
| C125379-50mg | 183133-96-2 | 询底价 |
| C125379-10mg | 183133-96-2 | 询底价 |
| C125379-25mg | 183133-96-2 | 询底价 |
属性
| 熔点 | 180°C |
| 溶解性 | DMSO > 125 mg/ml |
| 存贮条件 | 储存温度-20°C |
描述
| 产品介绍 | Cabazitaxel 是一种天然紫杉烷的半合成品衍生物。 |
| 备注 | Cabazitaxel (Jevtana, XRP6258) is a semi-synthetic derivative of a natural taxoid. |
| 生化机理 |
Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. Cabazitaxel binds to and stabilizes tubulin, resulting in the inhibition of microtubule depolymerization and cell division, cell cycle arrest in the G2/M phase, and the inhibition of tumor cell proliferation. Unlike other taxane compounds, this agent is a poor substrate for the membrane-associated, multidrug resistance (MDR), P-glycoprotein (P-gp) efflux pump and may be useful for treating multidrug-resistant tumors. In addition, cabazitaxel penetrates the blood-brain barrier (BBB). |
| 别名 | 7β,10β-二甲氧基多西紫杉醇;XRP6258; RPR-116258A; taxoid XRP6258 |
卡巴他赛信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于卡巴他赛报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途