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其他小分子
Zafirlukast
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
货号 | CAS号 | 操作 |
---|---|---|
Z129979-50mg | 107753-78-6 | 询价 |
Z129979-100mg | 107753-78-6 | 询价 |
Z129979-250mg | 107753-78-6 | 询价 |
产品介绍
- 分子量575.68
- MDL号 MFCD00864775
属性
溶解性 | Partly miscible in water. |
存贮条件 | 储存温度-20°C |
描述
应用 | A potent and selective CysLT1 receptor antagonist. |
产品介绍 | Zafirlukast是一种白三烯受体拮抗剂(LTRA),IC50为0.6μM,作用于CYP2C9,IC50为7.0 μM。 |
备注 | Zafirlukast is a leukotriene receptor antagonist (LTRA). (IC50=0.6μM, IC50=7.0 ?M for CYP2C9) |
生化机理 | Zafirlukast is a potent subtype specific cysteinyl leukotriene type 1 receptor (CysLT1) antagonist; antiasthmatic. The cysteinyl-leukotrienes (CysLTs), LTC4 and LTD4, are potent mediators of asthma and hypersensitivity. They induce bronchoconstriction, augment microvascular permeability, and are vasoconstrictors of coronary arteries. |
别名 | 扎鲁司特; 扎鲁斯特;N-[3-[[2-甲氧基-4-[[[(2-甲苯基)磺酰基]氨基]羰基]苯基]甲基]-1-甲基-1H-吲哚-5-基]氨基甲酸环戊酯; Accolate; Accoleit; Vanticon;Cyclopentyl N-[3-[[2-Methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]carbamate;Cyclopentyl [3-[2-Methoxy-4-[(o-tolylsulfonyl)carbamoyl]benzyl]-1-methyl-1H-indol-5-yl]carbamate;N-[3-[[2-Methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]carbamic Acid Cyclopentyl Ester;[3-[2-Methoxy-4-[(o-tolylsulfonyl)carbamoyl]benzyl]-1-methyl-1H-indol-5-yl]carbamic Acid Cyclopentyl Ester |
Zafirlukast信息由上海阿拉丁生化科技股份有限公司为您提供,如您想了解更多关于Zafirlukast报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途