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Phenylbutazone

品牌 厂商性质 产地 货期
阿拉丁 生产商 上海 现货

询价
产品参数
货号 CAS号 操作
P129990-100g 50-33-9 询价
P129990-5g 50-33-9 询价
P129990-25g 50-33-9 询价
P129990-500g 50-33-9 询价
产品介绍

  • 分子式 C19H20N2O2
  • 分子量308.37

属性

溶解性 Soluble in water (1 mg/ml at 25 °C), ethanol (62 mg/ml at 25 °C), methanol, DMSO (62 mg/ml at 25 °C), and DMF (25 mg/ml).

描述

应用 An inhibitor of Cox.
产品介绍 Phenylbutazone 是一种非甾体抗炎剂,用于治疗慢性疼痛,包括关节炎的症状。
备注 Phenylbutazone(Butazolidin, Butatron) is used as a non-steroidal anti-inflammatory agent for the treatment of chronic pain, including the symptoms of arthritis.
生化机理 Phenylbutazone is a compound of research interest as an anti-inflammatory and anti-proliferative agent. Several studies have investigated Phenylbutazone as an anti-inflammatory agent and its role in mediating prostaglandin synthesis. Phenylbutazone may be of interest regarding research into anti-proliferative effects as well, especially in colorectal cancer studies. In studies with human colon cancer cell lines investigating anti-proliferative capabilities of NSAIDs, Phenylbutazone was noted to have intermediate anti-proliferative potency as compared to other NSAIDs. Phenylbutazone is an inhibitor of Cox (cyclooxygenase) that is also a substrate for peroxidation by Cox.
别名 4-丁基-1,2-二苯基-3,5-吡唑烷二酮;保泰松;布他唑立丁;苯基丁氮酮;4-Butyl-1,2-diphenyl-3,5-pyrazolidinedione; 1,2-Diphenyl-3,5-dioxo-4-n-butylpyrazoline

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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途