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Pamidronate disodium salt hydrate
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
货号 | CAS号 | 操作 |
---|---|---|
P129944-50mg | 57248-88-1 | 询价 |
P129944-1g | 57248-88-1 | 询价 |
P129944-250mg | 57248-88-1 | 询价 |
产品介绍
属性
溶解性 |
|
存贮条件 | 储存温度 2-8°C |
描述
应用 | A farnesyl diphosphate synthase inhibitor. |
生化机理 | Pamidronate disodium salt is a bisphosphonate compound, which inhibits farnesyl diphosphate synthase and bone resorption. Studies suggest that Pamidronate disodium salt stimulates polymorphonuclear leukocyte and platelet derived nitric oxide production. It is believed that this nitric oxide production can lead to a negative feedback mechanism, which could restrict the inflammatory process and reduce bone resorption. Furthermore, bisphosphonates induce endothelial cell death, cancer cell apoptosis, and nuclear factor-κB pathway activation, via the endothelial protein C receptor. |
别名 | 帕米膦酸钠水合物; 3-氨基-1-羟基丙亚基-1,1-二磷酸二钠水合物;Aredia;3-Amino-1-hydroxypropane-1,1-diphosphonic acid disodium salt |
Pamidronate disodium salt hydrate信息由上海阿拉丁生化科技股份有限公司为您提供,如您想了解更多关于Pamidronate disodium salt hydrate报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途