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Pioglitazone
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| P129907-10mg | 111025-46-8 | 询价 |
| P129907-250mg | 111025-46-8 | 询价 |
| P129907-50mg | 111025-46-8 | 询价 |
产品介绍
属性
| 溶解性 | Soluble in water (<1 mg/ml at 25 °C), DMSO (15 mg/ml at 25 °C), DMF (2.5 mg/ml), ethanol (<1 mg/ml at 25 °C), and 1:1 solution of DMSO:PBS (pH 7.2) (~ 0.1 mg/ml). |
| 存贮条件 | 储存温度-20°C |
描述
| 应用 | A PPAR agonist with potential antidiabetic characteristics. |
| 产品介绍 | Pioglitazone 是一种选择性过氧化物酶体增殖物激活受体γ激动剂。 |
| 备注 | Pioglitazone (Actos) is a selective peroxisome proliferator-activated receptor gamma stimulator. |
| 生化机理 | Pioglitazone, a thaizolidinedione derivative, has been shown to be a high affinity ligand for the peroxisome proliferator-activated receptor (PPAR), specifically PPARγ1 and PPARα activator. Binding assays have indicated that this activation is due to direct binding of pioglitazone to each subtype. It has been noted that this agent promotes adipocyte differentiation of mesenchymal and preadipocyte stem cell lines In vitro. Additionally, pioglitazone is an inhibitor of NF κB. |
| 别名 | 匹格列酮; 5-[[4-[2-(5-乙基吡啶-2-基)乙氧基]苯基]甲基]-1,3-噻唑烷-2,4-二酮;Glustin; U 72107; Zactos;5-[[4-[2-(5-Ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione |
Pioglitazone信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Pioglitazone报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途