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Nadifloxacin
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| N129378-1g | 124858-35-1 | 询价 |
| N129378-250mg | 124858-35-1 | 询价 |
产品介绍
属性
| 熔点 | 245-251 °C |
| 敏感性 | 对热敏感 |
| 溶解性 | Soluble in DMSO (20 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C). |
| 存贮条件 | 储存温度-20°C |
描述
| 应用 | A fluoroquinolone broad spectrum antibiotic. |
| 生化机理 | Nadifloxacin is a cell-permeable, synthetic, broad-spectrum fluoroquinolone antibiotic that inhibits the growth of both gram-positive and gram-negative microbes. Studies suggest that the mechanism of inhibition occurs by interfering with DNA replication. Specifically Nadifloxacin suppresses gram-positive bacterial growth by targeting topoisomerase IV and suppresses gram-negative bacteria by inhibiting Topo II (DNA gyrase), which both function to relax postive supercoils before DNA replication. Furthermore, Nadifloxacin can decrease superoxide radical anions such as O2- and OH-, produced by neutrophils. |
| 别名 | 那氟沙星; 9-氟-8-(4-羟基-1-哌啶基)-5-甲基-1-氧-1,5,6,7-四氢吡啶并[3,2,1-ij]喹啉-2-羧酸;9-Fluoro-8-(4-hydroxy-1-piperidinyl)-5-methyl-1-oxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylic Acid;Acuatim; Nadixa; OPC7251 |
Nadifloxacin信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Nadifloxacin报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途