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Meloxicam

品牌 厂商性质 产地 货期
阿拉丁 生产商 上海 现货

询价
产品参数
货号 CAS号 操作
M129228-100g 71125-38-7 询价
M129228-25g 71125-38-7 询价
M129228-10g 71125-38-7 询价
M129228-5g 71125-38-7 询价
产品介绍

  • 分子式 C14H13N3O4S2
  • 分子量351.40

属性

熔点 255°C
敏感性 对热敏感
溶解性 Soluble in water (22 mg/ml), DMSO (25 mg/ml), DMF, acetone(slightly soluble), ethanol(slightly soluble), and methanol(slightly soluble).
存贮条件 储存温度 2-8°C

描述

应用 An inhibitor of Cox-1 and Cox-2, selective for Cox-2.
产品介绍 Meloxicam 是一种非甾体类抗炎剂,具有镇痛和降低发烧作用。
备注 Meloxicam (Mobic) is a nonsteroidal anti-inflammatory agent with analgesic and fever reducer effects.
生化机理 Meloxicam, a non-steroidal anti-inflammatory agent, has been reported to inhibit the inducible isoform of Cox-2. Meloxicam is an inhibitor selective for Cox-2 (IC50 of 4.7 μM) over Cox-1 (IC50 of 36.6 μM). Studies suggest that Meloxicam is Cox-2 preferential, therefore it will probably not display a lower gastrointestinal toxicity than non-selective anti-inflammatory agents. This compound has been shown to also inhibit prostanoid synthesis in inflammatory cells. Additionally, Meloxicam has demonstrated the ability to non-competitively inhibit erythrocyte PGD (6-phosphogluconate dehydrogenase) activity in vitro.
别名 美洛昔康;4-羟基-2-甲基-N-(5-甲基-2-噻唑基)-2H-1,2-苯并噻嗪-3-甲酰胺-1,1-二氧化物;UH-AC 62XX;Mobic; Metacam; UH-AC 62XX; Coxicam;4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-Dioxide

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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途