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MMAD
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| M125063-10mg | 203849-91-6 | 询价 |
| M125063-50mg | 203849-91-6 | 询价 |
| M125063-5mg | 203849-91-6 | 询价 |
产品介绍
- 分子式 C41H66N6O6S
- 分子量771.06
属性
| 溶解性 | 25°C: DMSO |
| 存贮条件 | 储存温度-20°C |
描述
| 产品介绍 | Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload and antibody drug conjugate. |
| 生化机理 | For comparison purposes, the ADC A1 -mc-MMAD and/or A1 -vc-MMAD were used. The linker payload, mc-MMAD (6-maleimidocaproyl-monomethylauristatin-D) was conjugated to the A1 anti-5T4 monoclonal antibody through a cysteine residue at a ratio of approximately 4 drug moieties per antibody molecule. The linker payload mc- Val-Cit-PABA-MMAD or vc-MMAD (maleimidocapronic -valine-citruline-p- aminobenzyloxycarbonyl- monomethylauristatin-D) was conjugated to the A1 anti-5T4 monoclonal antibody through a cysteine residue at a ratio of approximately 4 drug moieties per antibody molecule. |
| 别名 | 单甲基澳瑞他汀 D;Demethyldolastatin 10;Monomethylauristatin D;Monomethyl Dolastatin 10 |
MMAD信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于MMAD报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途