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Minisite
其他小分子
Levosimendan
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
货号 | CAS号 | 操作 |
---|---|---|
L129925-500mg | 141505-33-1 | 询价 |
L129925-1g | 141505-33-1 | 询价 |
L129925-50mg | 141505-33-1 | 询价 |
L129925-100mg | 141505-33-1 | 询价 |
L129925-250mg | 141505-33-1 | 询价 |
产品介绍
- 分子式 C14H12N6O
- 分子量280.28
- MDL号 MFCD00867135
属性
熔点 | 210-214 °C |
溶解性 | Soluble in water (<1 mg/ml), DMSO (56 mg/ml), methanol, and ethanol (<1 mg/ml). |
存贮条件 | 储存温度 2-8°C |
描述
应用 | A Ca2+ sensitizer that increases contractile force of the myocardium. |
产品介绍 | Levosimendan 是一种钙增敏剂,通过与cardiac troponin C (cTnC)结合而发挥作用,这种作用具有钙依赖性。 |
备注 | Levosimendan is a calcium sensitizer acting through calcium-dependent binding to cardiac troponin C (cTnC), provides treatment for heart failure. Phase 4. |
生化机理 | Levosimendan is a Ca2+ sensitizer that increases contractile force of the myocardium by enhancing the sensitivity of myofilaments to calcium without increasing intracellular calcium concentration. Levosimendan has been shown to reduce circulating proinflammatory cytokine interleukin-6 and soluble apoptosis mediators. Levosimendan is an inhibitor of PDE. |
别名 | 左西孟旦; 左旋西孟旦;OR1259; (-)-OR-1259; (R)-Simendan; 2-[2-[4-[(4R)-1,4,5,6-Tetrahydro-4-methyl-6-oxo-3-pyridazinyl]phenyl]hydrazinylidene]-propanedinitrile; OR 1259; (R)-((4-(1,4,5,6-Tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazono) propanedintrile;Simdax; Mesoxalonitrile (-)-(p((R)-1,4,5,6-tetrahydro-4-methyl-6- oxo-3-pyridazinyl)phenyl)hydrazone |
Levosimendan信息由上海阿拉丁生化科技股份有限公司为您提供,如您想了解更多关于Levosimendan报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途