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其他小分子
Leflunomide
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| L129518-5g | 75706-12-6 | 询价 |
| L129518-250mg | 75706-12-6 | 询价 |
| L129518-25g | 75706-12-6 | 询价 |
| L129518-50mg | 75706-12-6 | 询价 |
| L129518-1g | 75706-12-6 | 询价 |
产品介绍
- 分子式 C12H9F3N2O2
- 分子量270.21
- MDL号 MFCD00867593
- PubChem编号 24278516
属性
| 熔点 | 166.5 °C |
| 敏感性 | 对热敏感 |
| 溶解性 | Soluble in DMSO (54 mg/ml at 25 °C), ethanol (54 mg/ml at 25 °C), and water (<1 mg/ml at 25 °C). |
| 存贮条件 | 储存温度 2-8°C |
描述
| 应用 | An inhibitor of Cox-2 and tyrosine kinase. |
| 产品介绍 | Leflunomide是免疫抑制剂，其活性代谢产物为A77 1726(RS-61980)。 |
| 备注 | Leflunomide is an immunosuppressant agent. Its active metabolite is Teriflunomide. |
| 生化机理 | Leflunomide is an immunosuppressive drug that inhibits T and B cell responses. Leflunomide is an inhibitor of Cox-2, of tyrosine phosphorylation (tyrosine kinase), of DHODH (dihydroorotate dehydrogenase), an enzyme for de novo pyrimidine synthesis, and of TNF-dependent NF-κB activation. The physiological activity of leflunomide is attributed mainly to its metabolite A77 1726. |
| 别名 | 5-甲基-N-[4-(三氟甲基)苯基]异恶唑-4-甲酰胺;来氟米特;HWA486; RS-34821; SU101;5-Methyl-N-[4-(trifluoromethyl)phenyl]isoxazole-4-carboxamide;5-Methylisoxazole-4-(4-trifluoromethyl)carboxanilide;HWA486; RS-34821; SU101 |
Leflunomide信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Leflunomide报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途