普通会员
诚信认证：
工商注册信息已核实！
快速导航
产品分类
微信二维码
Minisite
QQ号咨询
其他小分子
Anastrozole
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| A126470-25g | 120511-73-1 | 询底价 |
| A126470-500mg | 120511-73-1 | 询底价 |
| A126470-100mg | 120511-73-1 | 询底价 |
| A126470-5g | 120511-73-1 | 询底价 |
| A126470-1g | 120511-73-1 | 询底价 |
产品介绍
- 分子式 C17H19N5
- 分子量293.37
属性
| 溶解性 | Soluble in chloroform, methanol, ethanol (59 mg/ml at 25 °C), DMSO (59 mg/ml at 25 °C), and DMF (~14 mg/ml). |
| 存贮条件 | 储存温度-20°C |
描述
| 产品介绍 | Anastrozole is known to inhibit the CYP19 enzyme (aromatase, IC50 = 15 nM) that converts androgens to estrogens. Anastrozole has been seen to reversibly bind to the CYP19 enzyme through competitive inhibition. |
| 备注 | Anastrozole is a third-generation nonsteroidal selective aromatase inhibitor. |
| 生化机理 |
Anastrozole is a potent and highly selective aromatase (CYP19) inhibitor (IC50 = 15 nM) that has no discernible effect on adrenocorticoid hormone synthesis. Anastrozole reduces plasma estrogen levels and exhibits antitumor activity in vivo. Orally active. |
| 别名 | 阿那曲唑;ICI-D1033;2;2"-[5-(1H-1;2;4-Triazol-1-ylmethyl)-1 3-Phenylene]bis(2-methyl-propiononitrile、 Arimidex;ZD1033 a,a,a′,a′-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetonitrile |
Anastrozole信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Anastrozole报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途