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AMG-900
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| A129924-10mg | 945595-80-2 | 询价 |
| A129924-1mg | 945595-80-2 | 询价 |
| A129924-50mg | 945595-80-2 | 询价 |
| A129924-5mg | 945595-80-2 | 询价 |
产品介绍
属性
描述
| 生化机理 |
AMG 900 is a novel potent and highly selective Pan-aurora kinase inhibitor with an IC50 of median 3.5 nM. AMG 900 repressed autophosphorylation of aurorakinases A and B as well as the phosphorylation of histone H3.The predominant cellular response of tumor cells to AMG 900treatment is aborted cell division without a mitotic arrest, which leads to endoreduplication and cell death. AMG 900 was originally developed by Amgen. A phase 1 first-in-human study evaluating AMG 900 in advanced solid tumors is currently recruiting participants. |
AMG-900信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于AMG-900报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途