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DMAT
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| D127353-250mg | 749234-11-5 | 询价 |
| D127353-10mg | 749234-11-5 | 询价 |
| D127353-50mg | 749234-11-5 | 询价 |
产品介绍
属性
| 溶解性 | DMSO |
| 存贮条件 | 储存温度-20°C |
描述
| 产品介绍 | DMAT 是一种有效的，特异性的 CK2 抑制剂，IC50 值为 130 nM |
| 生化机理 | Casein kinase II inhibitor II (Ck2 Inhibitor II) is a high affinity ATP-competitive inhibitor of casein kinase II. Ck2 Inhibitor II inhibits CK2 in rat liver with 1,300-fold greater selectivity for CK2 than for CK1 (IC50 = 140 nM and >200 μM respectively). Ki = 40 nM; In Jurkat human T-cell leukemia cells, Ck2 Inhibitor II does not display side effects on mitochondria polarization at concentrations up to 10 μM; Ck2 Inhibitor II is useful for in vivo studies due to cell permeability and high efficacy in cultured cells and has implications in research and treatment of neoplasia and infective diseases, in which CK2 plays a role and is highly active constitutively. |
| 别名 | 2-二甲基氨基-4,5,6,7-四溴苯并咪唑;Casein kinase II Inhibitor；CK2 Inhibitor；CK2 Inhibitor II； 2-Dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole；4,5,6,7-Tetrabromo-N,N-dimethyl-1H-benzimidazol-2-amine；4,5,6,7-Tetrabromo-N,N-dimethyl-1H-benzo[d]imidazol-2-amine； |
DMAT信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于DMAT报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途