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蛋白酶
Lopinavir
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| L299096-10mg | 192725-17-0 | 询价 |
| L299096-50mg | 192725-17-0 | 询价 |
| L299096-1g | 192725-17-0 | 询价 |
| L299096-250mg | 192725-17-0 | 询价 |
| L129320-100mg | 192725-17-0 | 询价 |
| L129320-250mg | 192725-17-0 | 询价 |
| L129320-1g | 192725-17-0 | 询价 |
| L129320-50mg | 192725-17-0 | 询价 |
| L129320-10mg | 192725-17-0 | 询价 |
产品介绍
属性
| 熔点 | 124-127 °C |
| 溶解性 | Soluble in DMF (~14 mg/ml), methanol, DMSO (126 mg/ml at 25 °C), water (< 1 mg/ml at 25 °C), and ethanol (126 mg/ml at 25 °C). |
| 存贮条件 | 储存温度 -20°C |
描述
| 应用 | Lopinavir has been used as a ZMPSTE24 and human immunodeficiency virus protease inhibitor. |
| 产品介绍 | Lopinavir is an antiviral HIV Protease Inhibitor. Lopinavir has insufficient bioavailability alone, so it is used in therapy in combination with Ritonavir, a HIV protease inhibitor, which inhibits cytochrome P450-3A4 (CYP3A4), a liver enzyme that normally metabolizes protease inhibitors. Lopinavir also has an ability to inhibit ZMPSTE24 (zinc metallopeptidase STE24). |
| 生化机理 | Lopinavir is an antiretroviral of the protease inhibitor class. Inhibition of HIV-1 protease prevents cleavage of the viral polyprotein precursor and results in the release of immature, noninfectious virions. A component of combination therapy to treat HIV/AIDS. |
| 别名 | ABT-378;洛匹那韦;洛吡那韦;(2S)-N-[(2R,4S,5S)-5-[[2-(2,6-二甲基苯氧基)乙酰]氨基]-4-羟基-1,6-二苯基-己-2-基]-3-甲基-2-(2-氧代-1,3-二氮杂环己-1-基)丁酰胺ABT-378;Aluviran;Koletra;ABT 378;ABT378;(2S)-N-[(2R,4S,5S)-5-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenyl-hexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide；(aS)-N-[(1S,3S,4S)-4-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-Pyrimidineacetamide; |
Lopinavir信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Lopinavir报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途