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蛋白酶
Nafamostat Mesylate
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| N129262-10mg | 82956-11-4 | 询价 |
| N129262-250mg | 82956-11-4 | 询价 |
| N129262-50mg | 82956-11-4 | 询价 |
产品介绍
- 分子式 C19H17N5O2·2CH4O3S
- 分子量539.58
- Beilstein号
- EC号
- MDL号 MFCD00941430
- PubChem编号
属性
| 熔点 | 260 °C |
| 溶解性 | Soluble in DMSO (>10 mg/ml), water (25 mg/ml) Note: Phosphate-containing buffers may cause precipitation, and ethanol (<1 mg/mL) at 25 °C. |
| 存贮条件 | 储存温度 2-8°C |
描述
| 应用 | A highly effective tryptase inhibitor. |
| 产品介绍 | Nafamostat Mesylate是一种抗凝血剂。 |
| 备注 | Nafamostat Mesylate is an anticoagulant. |
| 生化机理 | Nafamostat mesylate is a highly effective tryptase (Ki=95.3 pM) inhibitor. The compound has the ability to promote synthesis of interferon-γ, tumor necrosis factor-α, IL-12, and IL-18. Additionally, Nafamostat mesylate can induce production of intercellular adhesion molecules-1, B7.1, B7.2, CD40 and CD40 ligand in human blood mononuclear cells. Nafamostat mesylate is an anticoagulant and has been shown to decrease levels of plasma myeloperoxidase, and has also been used in ERCP pancreatitis studies. Nafamostat mesylate is an inhibitor of Factor X, Factor XII, granzyme A and KLK. |
| 别名 | 萘莫司他甲磺酸盐;甲磺酸萘莫司他; FUT-175;6-脒基-2-萘基 4-胍基苯甲酸酯甲基磺酸盐;Coahibitor; FUT-175; Futhan;6-Amidino-2-naphthyl 4-Guanidinobenzoate Bis(methanesulfonate);4-Guanidinobenzoic Acid 6-Amidino-2-naphthyl Ester Bis(methanesulfonate) |
Nafamostat Mesylate信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Nafamostat Mesylate报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途