诚信认证：
工商注册信息已核实！
快速导航
产品分类
微信二维码
Minisite
QQ号咨询
蛋白酶
Atazanavir Sulfate
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| A129321-10mg | 229975-97-7 | 询价 |
| A129321-1g | 229975-97-7 | 询价 |
| A129321-250mg | 229975-97-7 | 询价 |
| A129321-50mg | 229975-97-7 | 询价 |
| A129321-5mg | 229975-97-7 | 询价 |
产品介绍
属性
| 溶解性 | Soluble in water (4-5 mg/ml), and methanol. |
| 存贮条件 | 储存温度 2-8°C |
描述
| 应用 | A sulfate salt form of atazanavir that is an highly potent HIV-1 protease inhibitor. |
| 产品介绍 | Atazanavir Sulfate是一种HIV protease（HIV蛋白酶）抑制剂，抑制HIV Atazanavir，Ki值为2.66 nM。 |
| 备注 | Atazanavir is a HIV protease inhibitor with Ki of 2.66 nM. |
| 生化机理 | Atazanavir sulfate is a sulfate salt form of atazanavir that is an highly potent HIV-1 protease inhibitor. Has shown to be generally more potent than the five currently approved HIV-1 Prt inhibitors. Atazanavir (BMS-232632) inhibited the proteolytic cleavage of the viral gag precursor p55 polyprotein in a dose-dependent manner, with a EC50 of approximately 47 nM. Also highly selective for HIV-1 Prt and exhibits cytotoxicity only at concentrations 6,500- to 23,000-fold higher than that required for anti-HIV activity. Atazanavir (BMS-232632) may be an effective HIV-1 inhibitor that may be utilized in a variety of different drug combinations. |
| 别名 | BMS-232632-05;阿扎那韦硫酸盐;BMS-232632-05; Reyataz;BMS 232632 sulfate; BMS-232632 sulfate; BMS232632 sulfate;Methyl N-[(2S)-1-[[(2S,3S)-3-hydroxy-4-[[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-[(4-pyridin-2-ylphenyl)methyl]amino]-1-phenylbutan-2-yl]amino]-3,3-dimethyl-1-oxobutan-2-yl]carbamate sulfate |
Atazanavir Sulfate信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Atazanavir Sulfate报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途