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Lapatinib
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| L126696-250mg | 231277-92-2 | 询价 |
| L126696-500mg | 231277-92-2 | 询价 |
| L126696-100mg | 231277-92-2 | 询价 |
| L126696-5g | 231277-92-2 | 询价 |
| L126696-1g | 231277-92-2 | 询价 |
| L126696-25mg | 231277-92-2 | 询价 |
产品介绍
属性
| 溶解性 | DMSO 100 mg/mL (172.09 mM); Water <1 mg/mL (<1 mM); Ethanol <1 mg/mL (<1 mM) |
| 存贮条件 | 储存温度2-8℃ |
描述
| 应用 | An antineoplastic agent used in breast cancer research |
| 产品介绍 | Lapatinib可形成Lapatinib的二甲苯磺酸盐，是一种有效的EGFR和ErbB2抑制剂，IC50分别为10.2和9.8 nM。 |
| 备注 | Lapatinib, used in the form of Lapatinib Ditosylate, is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM, respectively. |
| 生化机理 | Lapatinib is an antineoplastic agent used in breast cancer research research. It appears to be a tyrosine kinase inhibitor which interrupts the Neu/ ErbB2 and EGFR (epidermal growth factor receptor) pathways, thus inhibiting ErbB-overexpressing tumors. Lapatinib binds to the ATP-binding pocket of the protein kinase domains on EGFR/ErbB, preventing self-phosphorylation in solid tumor cells. Lapatinib is an inhibitor of EGFR and Neu/ ErbB2. |
| 别名 | 拉帕替尼;N-[3-氯-4-[(3-氟苯基)甲氧基]苯基]-6-[5-[(2-甲磺酰乙基氨基)甲基]-2-呋喃基]喹唑啉-4-胺;Tykerb;GW572016;GW-572016;GW 572016;N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]-2-furyl]quinazolin-4-amine |
Lapatinib信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Lapatinib报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途