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激酶
Fenretinide
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| F126912-100mg | 65646-68-6 | 询价 |
| F126912-250mg | 65646-68-6 | 询价 |
| F126912-25mg | 65646-68-6 | 询价 |
| F126912-50mg | 65646-68-6 | 询价 |
| F126912-10mg | 65646-68-6 | 询价 |
产品介绍
- 分子式 C26H33NO2
- 分子量391.55
- MDL号 MFCD00792674
- PubChem编号 24278472
属性
| 敏感性 | 对热和空气敏感 |
| 溶解性 | Soluble in DMSO (25 mg/ml), ethanol (25 mg/ml)), chloroform, and acetone (easily soluble). |
| 存贮条件 | 储存温度 -20°C,充氩保存 |
描述
| 应用 | An agonist displaying activity at retinoid receptors |
| 产品介绍 | Fenretinide (4-HPR)是合成的维甲酸衍生物，能结合维甲酸受体（RAR）。 |
| 生化机理 | 4-Hydroxyphenylretinamide (Fenretinide) is a synthetic retinoid analog of all trans retinoic acid, which displays antiproliferative effects on cultured human breast cancer cells. In addition, 4-Hydroxyphenylretinamide functions as a selective activator of RAR (retinoid receptors). Studies involving lymphoid and myeloid malignant cell lines indicate that 4-Hydroxyphenylretinamide can induce apoptosis and reduce cell growth. These studies suggest that 4-Hydroxyphenylretinamide and all trans retanoic acid may bind to two different receptors to induce apoptosis. |
| 别名 | 4-HPR;全反式-N-(4-羟苯基)维甲酸;维甲酸对羟基苯胺;芬维A胺;维甲酰酚胺;4-HPR; (4-Hydroxyphenyl)retinamide; N-(4-Hydroxyphenyl)retinamide;all-trans-N-(4-Hydroxyphenyl)retinamide;Retinoic acid p-hydroxyanilide;4-Hydroxyphenylretinamide |
Fenretinide信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Fenretinide报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途