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抗生素
艾菲地可宁
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| A102398-10mg | 38966-21-1 | 询底价 |
| A102398-1mg | 38966-21-1 | 询底价 |
| A102398-5mg | 38966-21-1 | 询底价 |
产品介绍
- 分子式 C20H34O4
- 分子量338.48
- Beilstein号 4689958
- EC号 MFCD00083214
- MDL号 MFCD00083214
- PubChem编号 24890452
属性
| 敏感性 | 对光敏感 |
| 溶解性 | Soluble in ethanol (1 mg/ml,stable at least a week at 4°C.), DMSO (10 mg/ml,stable at least six weeks at -20°C.), and methanol (10 mg/ml). Insoluble in water. |
| 存贮条件 | 储存温度2-8°C |
| 密度 | 1.2200 |
描述
| 应用 | A novel tetracyclic diterpene antibiotic and also a DNA synthesis inhibitor in eukaryotes |
| 产品介绍 | Aphidicolin is a tetracyclic diterpene antibiotic and DNA synthesis inhibitor isolated from Cephalosporium aphidicola. Aphidicolin is reported to specifically inhibit DNA polymerase α and δ via binding to the enzyme, in eukaryotic cells such as the HeLa cell line, without affecting other DNA polymerases. This compound blocks the cell cycle at early S phase and has been reported to be useful for synchronizing cell cycles in cultured eukaryotic cells. This compound is also noted to induce apoptosis in HeLa S3 cells after 18-24 hours of the cell cycle. |
| 别名 | Aphidicolin;APC |
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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途