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抗生素
红霉素
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| E105345-100g | 114-07-8 | 询价 |
| E105345-25g | 114-07-8 | 询价 |
| E105345-5g | 114-07-8 | 询价 |
产品介绍
- 分子式 C37H67NO13
- 分子量733.93
- Beilstein号 75279
- EC号 204-040-1
- MDL号 MFCD00084654
- PubChem编号 24894626
属性
| 熔点 | 138-140°C |
| 旋光率 | -74 ° (C=2, EtOH) |
| 敏感性 | 对湿度敏感 |
| 溶解性 | 熔于乙醇、甲醇、丙酮、氯仿、乙腈和乙酸乙酯，中等程度溶于醚、二氯甲烷和乙酸戊酯。难溶于水。微有引湿性，无臭，味苦。遇酸不稳定。水中溶解度:+/- 3 MG/ML。 |
| 存贮条件 | 充氩保存 |
| 密度 | 1.2000 |
描述
| 应用 |
A macrolide antibiotic protein synthesis inhibitor. Erythromycin is an antibiotic produced by growth of certain strains of Streptomyces erythreus. This product is composed largely of erythromycin A with small amounts of erythromycins B and C and is recommended for concentration at 100 mg/L. Concentrations between 50 and 200 mg/L have also proven effective in controlling bacterial growth. Erythromycin has been used as a motilin receptor agonist, to block respiratory glycoconjugate secretion in human airways in vitro, and for selecting plasmid-cured and recombinant lactococcus lactis MG1363 strains. |
| 产品介绍 | Erythromycin is a potent macrolide inhibitor of CYP3A4 with antiinflammatory and prokinetic properties. Macrolides belong to a group of antibiotics that bind to the 50S ribosomal subunit and inhibit protein synthesis. Erythromycin is derived from Streptomyces erythreus and has been shown to inhibit NF-κB transcriptional activation, which leads to the inhibition of cytokine gene expression of IL-8 and lL-6. This mechanism was shown to occur via calcineruin-independent signaling T lymphocytes. |
| 备注 |
此产品所配溶液37°C只能保存3天，因此其储存溶液必须2-8°C保存. This product is soluble in water at 2 mg/mL, with a 0.067% solution in water yielding a pH of 8.0-10.5. It is also soluble in ethanol at 50 mg/mL, yielding a clear, colorless to faint yellow solution. It is freely soluble in alcohol, acetone, chloroform, acetonitrile and ethyl acetate but forms salts with acids. All solutions should be protected from light. |
| 生化机理 |
在转肽步骤抑制延长期，靠结合到核糖体上抑制细菌蛋白合成，对细菌诱发红霉素抗性。抗菌谱: 革兰氏阴性和阳性细菌。 属大环内酯抗生素（Macrolide antibiotic） |
| 别名 | 红霉素;红霉素碱;(-)-Erythromycin ;Abomacetin |
红霉素信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于红霉素报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途