普通会员
诚信认证:
工商注册信息已核实!
![](https://img.antpedia.com/cbook/dist_templates/0/images/icon14.png)
快速导航
产品分类
微信二维码
![](https://cbook.antpedia.com/attachments/design/6751/1682393653-0588.jpg)
Minisite
抗生素
巴佛洛霉素A1
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
货号 | CAS号 | 操作 |
---|---|---|
B101389-1mg | 88899-55-2 | 询底价 |
B101389-5mg | 88899-55-2 | 询底价 |
产品介绍
- 分子式 C35H58O9
- 分子量622.83
- Beilstein号 4730700
- MDL号 MFCD06795130
- PubChem编号 24891613
属性
敏感性 | 对热和光线敏感 |
溶解性 | Soluble in methanol, ethanol (0.1 mg/ml), DMSO (0.1 mg/ml), acetone, and chloroform. Insoluble in water., |
存贮条件 | 储存温度: -20 ℃;充氩保存 |
密度 | 1.1200 |
描述
应用 | A macrolide antibiotic and potent and selective inhibitor of vacuolar-type (v-type) H+ ATPase |
产品介绍 | Bafilomycin A1 is a potent and selective inhibitor of V-ATPase (vacuolar-type (v-type) H+ ATPase) and belongs to a class of membrane ATPase inhibitors. The compound can inhibit E1E2 ATPases from sarcoplasmic reticulum, Escherichia coli, and ox brain versus F1F0 ATPases found in bacteria and mitochondria. Some of the more bafilomycin A1 affected ATPases include Neurospora and plant vacuoles, as well as chromaffin granules. Additionally, Bafilomycin A1 prevents lysosomal cholesterol trafficking in macrophages and can be used to distinguish different types of ATPases. Research shows that Bafilomycin A1 can inhibit macroautophagy and promote apoptosis in colon cancer cells. |
生化机理 | 动物细胞、植物细胞和微生物液泡型H+-ATP酶(V-ATP酶)的特异性抑制剂。 |
别名 | ; |
巴佛洛霉素A1信息由上海阿拉丁生化科技股份有限公司为您提供,如您想了解更多关于巴佛洛霉素A1报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途