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抗生素

蛎灰菌素A

品牌 厂商性质 产地 货期
阿拉丁 生产商 上海 现货

询价
产品参数
货号 CAS号 操作
V102390-5mg 21411-53-0 询价
产品介绍

属性

溶解性 Soluble in water (partly), ethanol (4%), methanol (4%), DMF, and DMSO.
存贮条件 储存温度-20°C
密度 1.2600

描述

应用 A bacteriostatic inhibitor of translation at the 50S ribosome
产品介绍 Ostreogrycin A, also known as Virginiamycin M1, is a streptogramin macrolide antibiotic. Ostreogrycin A interacts with the bacterial 50S ribosome, inhibiting its function in a reversible manner. Activity of Ostreogrycin A at the ribosome blocks translation and produces a bacteriostatic effect. With addition of Virginiamycin S1 , the two antibiotics produce a synergistic bacteriocidal effect. The combination of these compounds, available as a Virginimycin complex , demonstrate efficacy against a broad range of bacteria.
生化机理 Virginiamycin M1 inhibits bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation. It inactivates the 50S ribosome. S. virginiae inactivates VM1 by reducing its 16-carbonyl group, forming 16R-dihydroVM1. VM1 reductase participates solely in VM1 inactivation in vivo
别名 春霉素 A;Mikamycin A;Staphylomycin

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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途