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抗生素
缬氨霉素
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| V100895-50mg | 2001-95-8 | 询价 |
| V100895-5mg | 2001-95-8 | 询价 |
| V100895-10mg | 2001-95-8 | 询价 |
产品介绍
- 分子式 C54H90N6O18
- 分子量1111.32
- Beilstein号 78657
- EC号 217-896-6
- MDL号 MFCD00005114
- PubChem编号 24881872
属性
| 熔点 | 190°C |
| 敏感性 | 对光、湿度敏感 |
| 溶解性 | Soluble in ethanol (50 mg/ml), DMSO (≥10 mg/ml), petroleum ether, ether, benzene, chloroform, glacial acetic, butyl acetate, and methanol (5 mg/ml). Insoluble in water |
| 存贮条件 | 储存温度-20°C |
| 密度 | 1.0600 |
描述
| 应用 |
A potassium ionophore shown to induce cell death;Being a Potassium selective ionophore, valinomycin is used in specific potassium measurment electrodes. Valinomycin is an apoptosis inducer. It is used as a tool in membrane research |
| 产品介绍 | Valinomycin is a cyclodepsipeptide and potassium ionophore that has been shown to induce cell death. The compound has been shown to have antibabesial activity and reported to promote hemolysis in HK erythrocytes, and decrease the intracellular ATP concentration. CHO cell studies demonstrate that cells exposed to Valinomycin display caspase-3 activation, phosphatidylserine membrane translocation, and mitochondrial membrane depolarization. Can be used as a biosensor to detect potassium efflux as well. |
| 生化机理 | K+-selective ionophoric cyclodepsipeptide; potassium ionophore which uncouples oxidative phosphorylation, induces apoptosis in murine thymocytes, inhibits NGF-induced neuronal differentiation and antagonizes ET-induced vasoconstriction |
| 别名 | 缬氨霉素 ;Cyclo(L-Val-D-HyIva-D-Val-L-Lac-)3: HyIva = α-Hydroxyisovaleric acid, Lac = Lactic acid |
缬氨霉素信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于缬氨霉素报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途