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抗生素
硫藤黄素
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| T102393-1mg | 87-11-6 | 询价 |
| T102393-25mg | 87-11-6 | 询价 |
| T102393-5mg | 87-11-6 | 询价 |
产品介绍
- 分子式 C8H8N2O2S2
- 分子量228.29
- MDL号 MFCD07370147
属性
| 敏感性 | 对光敏感 |
| 溶解性 | Soluble in DMSO (5 mg/ml), and water (210 mg/L). |
| 存贮条件 | 储存温度-20°C |
描述
| 应用 | An RNA polymerase inhibitor and suppressor of tumor cell-induced angiogenesis |
| 产品介绍 | Thiolutin is an RNA polymerase inhibitor, and a sulfur-based microbial antibiotic generated by Streptomyces sp. The compound has been shown to inhibit transcription in Saccharomyces cerevisiae and mRNA degradation. Thiolutin inhibits the adhesion of endothelial cells, including adhesion of human umbilical vein endothelial cells (HUVECs) to vitronectin, and restricts tumor cell-induced angiogenesis. Studies have reported that Thiolutin is an effective inducer of HSP 27 (heat shock protein 27; Hsp27) phosphorylation. Research shows that in the presence of Thiolutin, the interaction between Hsp27 and nestin is disrupted, which results in the breakdown of nestin filaments. |
| 别名 | Thiolutin;Farcinicin; N-(4,5-Dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl); Propiopyvothine;Acetopyrrothine |
硫藤黄素信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于硫藤黄素报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途