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抗生素
硫链丝菌肽
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| T102394-250mg | 1393-48-2 | 询价 |
| T102394-1g | 1393-48-2 | 询价 |
产品介绍
- 分子式 C72H85N19O18S5
- 分子量1664.89
- Beilstein号
- EC号 215-734-9
- MDL号 MFCD00135828
- PubChem编号 24900569
属性
| 熔点 | 246-256℃ |
| 溶解性 | Soluble in DMSO (10 mg/ml), chloroform (10 mg/ml), dioxane, pyridine, glacial acetic acid, and DMF. Insoluble in water |
| 存贮条件 | 储存温度:-20℃ |
| 密度 | 1.6400 |
描述
| 应用 | A protein synthesis-inhibiting antibiotic |
| 产品介绍 | Thiostrepton is a cyclic peptide antibiotic, densely packed with thiazoles and other structurally intriguing moieties. Thiostrepton exhibits antibiotic activity through blockade of ribosome turnover after an elongation step in protein synthesis by inhibiting both the dissociation of elongation factor G (EF-G) from the ribosome and the release of inorganic phosphate from EF-G following GTP hydrolysis. Thiostrepton is also described to show efficacy against cancer cell growth through downregulation of the forkhead box M1 (FOXM1) transcription factor, commonly overexpressed in many malignancies. Thiostrepton is an inhibitor of FOXM1 |
| 生化机理 | 肽抗生素，阻止延长因子G（EF-G）和GTP结合到50S核糖体亚单元上 |
| 别名 | 硫链丝菌素;Bryamycin; Thiactin; Alaninamide;FOXM1 Inhibitor I, FOXM1 Inhibitor I |
硫链丝菌肽信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于硫链丝菌肽报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途