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抗生素
Stauprimide
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| S139814-1mg | 154589-96-5 | 询价 |
| S139814-5mg | 154589-96-5 | 询价 |
产品介绍
- 分子式 C35H28N4O5
- 分子量584.62
属性
| 熔点 | 145°C |
| 敏感性 | 对光敏感 |
| 溶解性 | Soluble in ethanol (slightly), methanol, DMSO (100 mg/ml), DMF, and water (limited). |
| 存贮条件 | 储存温度 -20°C |
描述
| 应用 | An indolocarbazole promoter of embryonic stem cell differentiation. |
| 产品介绍 | Stauprimide is an indolocarbazole semi-synthetic small molecule shown to significantly increase the efficiency of directed embryonic stem cell differentiation. Stauprimide inhibits the nuclear localization of NME2, blocking and downregulating c-Myc expression. The expression of c-Myc is crucial for embryonic stem cell self-renewal, and intervention by Stauprimide allows for more efficient lineage-specific differentiation. NME2 is also indicated to be upregulated in certain cancers, indicating further application for the blocking action of Stauprimide |
| 生化机理 | Stauprimide is an enhancer stem cell differentiation into endoderm. In vitro differentiation of embryonic stem cells is of great interest to regenerative medicine, and current protocols are labor-intensive and expensive. Small molecules that induce or enhance differentiation are highly desired. High-content screening identified compounds that enhance endodermal differentiation in the presence of low levels of Activin A. Stauprimide increased definitive endodermal markers but not markers for visceral/parietal endoderm or mesoderm. Stauprimide-Stauprimide is an enhancer stem cell differentiation into endoderm. In vitro differentiation of embryonic stem cells is of great interest to regenerative medicine, and current protocols are labor-intensive and expensive. Small molecules that induce or enhance differentiation are highly desired. High-content screening identified compounds that enhance endodermal differentiation in the presence of low levels of Activin A. Stauprimide increased defin |
| 别名 | ;N-Benzoyl-7-oxostaurosporine |
Stauprimide信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Stauprimide报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途