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抗生素

D-青霉胺

品牌 厂商性质 产地 货期
阿拉丁 生产商 上海 现货

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产品参数
货号 CAS号 操作
P115952-100g 52-67-5 询底价
P115952-25g 52-67-5 询底价
P115952-5g 52-67-5 询底价
产品介绍

属性

沸点 251.8° C
熔点 210° C
折光率 1.53
旋光率 -63o
溶解性 Soluble in water (30 mg/ml at 25° C), ethanol (<1 mg/ml at 25° C), methanol, and DMSO (<1 mg/ml at 25° C)
存贮条件 储存温度2-8℃
密度 1.2000

描述

应用 It is used as an antirheumatic and as a chelating agent in Wilson′s disease. It is used as a copper chelator to form mixed disulfides with cysteine or other sulfide media components. It is used to inactivate protein-1 DNA binding and to inhibit the growth of asynchronous cultures of rabbit articular chondrocytes.
产品介绍 Penicillamine is an exogenous NOS modulator, found to inhibit urease activity.
生化机理 Penicillamine is a characteristic degradation product of penicillin type antibiotics. One atom of copper combines with two molecules of penicillamine. Penicillamine reduces excess cystine excretion in cystinuria. This is by disulfide interchange between penicillamine and cystine, which results in formation of a readily excreted penicillamine-cysteine disulfide. Penicillamine interferes with the formation of cross-links between tropocollagen molecules and cleaves them when newly formed. Penicillamine lowers IgM rheumatoid factor and depresses T-cell activity.
别名 3,3-二甲基-D-半胱氨酸; 3-巯基-D-缬氨酸; D-(-)-2-氨基-3-巯基-3-甲基丁酸; 二甲基半胱胺酸; β-巯基缬氨酸; D-(-)-青霉胺;Cuprimine; 3-Mercapto-D-valine; Mercaptovaline; Penicillamine; D-β,β-Dimethylcysteine; D-(?)-2-Amino-3-mercapto-3-methylbutanoic acid; D-β-Mercaptovaline;3,3-Dimethyl-D-cysteine

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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途