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抗生素

棒曲霉素

品牌 厂商性质 产地 货期
阿拉丁 生产商 上海 现货

询价
产品参数
货号 CAS号 操作
P113515-5mg 149-29-1 询价
P113515-1mg 149-29-1 询价
P113515-25mg 149-29-1 询价
产品介绍

属性

熔点 108-111°C
溶解性 Soluble in water, 100% ethanol (25 mg/mL), ethyl acetate (50 mg/mL), amyl acetate, DMSO (10 mg/mL), acetone, ethyl ether (sparingly), benzene (sparingly), and dichloromethane (10 mg/mL)
存贮条件 储存温度-20°C
密度 1.5200

描述

应用 An inhibitor of protein prenylation
产品介绍 Patulin, a mycotoxin, has been reported to contain antibiotic characteristics. This compound displays the ability to specifically inhibit Na+-K+ ATPase. In murine studies, Patulin was found to inhibit protein prenylation in cells. Mechanistic studies suggest that Patulin reduces incorporation of mevalonate into proteins and prevents protein transferase action, which is required for protein prenylation. Additional experiments show that this mycotoxin also inhibits cell-free microtubule polymerization by covalently reacting with thiol groups of microtubule proteins.
别名 4-羟基-4H-呋[3,2-c]吡喃-2(6H)-酮;4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one

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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途