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抗生素
寡霉素A 来源于 淀粉酶产色链霉菌
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| O102388-5mg | 579-13-5 | 询价 |
| O102388-25mg | 579-13-5 | 询价 |
产品介绍
- 分子式 C45H74O11
- 分子量791.06
- Beilstein号 5702132
- EC号 209-437-3
- MDL号 MFCD00065705
- PubChem编号 24886820
属性
| 溶解性 | Soluble in DMSO (300 mg/ml), ethanol (200 mg/ml), acetone (800 mg/ml), glacial acetic acid (37.5 g/100ml) at 25 °C, water (2 mg/100ml) at 25 °C, ether (28 g/100ml) at 25 °C, and benzene (6 g/100ml) at 25 °C. |
| 存贮条件 | 储存温度:-20 ℃ |
| 密度 | 1.1400 |
描述
| 应用 | Oligomycin is used to inhibit membrane bount mitochondrial ATP synthase. It is used to inhibit sucrose synthesis and 14C translocation in sunflower leaves, to study antibiotic resistance, and to study carotid chemoreceptor responses to O2 and CO2 in the cat. |
| 产品介绍 | Oligomycin A inhibits ATP5 (mitochondrial ATPases, F1F0) bound to the cell membrane. This compound stimulates lysosome acidification due to shunting of membrane potential at a concentration of 1.5-3 μM. The compound has been observed to Induce apoptosis in a variety of cell types along with inducing a switch from the apoptotic to necrotic pathway. It also exhibits broad nematocidal, antifungal, and antitumor activities. Oligomycin A has caused dissipated mitochondrial membrane potential, decreased cytoplasmic ATP contents and disassembled metaphase II oocyte spindles when introduced to mouse oocytes. |
| 备注 | 来源于淀粉酶产色链霉菌 |
| 生化机理 | Oligomycin inhibits membrane bound mitochondrial ATP synthase (ATPase), proton channel (pump, FO subunit) blockers thereby inhibiting oxidative phosphorylation and the electron transport chain. |
| 别名 | Oligomycin A;MCH 32;MCH 32 |
寡霉素A 来源于 淀粉酶产色链霉菌信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于寡霉素A 来源于 淀粉酶产色链霉菌报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途