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抗生素

无活菌素 来源于灰色链霉菌变种

品牌 厂商性质 产地 货期
阿拉丁 生产商 上海 现货

询价
产品参数
货号 CAS号 操作
N139792-25mg 6833-84-7 询价
N139792-5mg 6833-84-7 询价
N139792-100mg 6833-84-7 询价
产品介绍

  • 分子式 C40H64O12
  • 分子量736.93 (for Nonactin)

属性

熔点 145℃ - 146℃
敏感性 对湿度敏感
溶解性 Soluble in chloroform (9.80 - 10.20 mg/ml), ethanol (10 mM), DMSO (10 mg/ml), and methanol. Insoluble in water.
存贮条件 储存温度-20°C,充氩储存

描述

应用 Nonactin has an inhibitory effects on the P170 glycoprotein-mediated efflux of chemotherapeutic agents in multiple-drug-resistant cancer cells.
Nonactin, a natural mixture of macrotetrolides, was used in agriculture under the name trade POLYNACTIN.

Nonactin has been reported to specifically inhibit the processing of cytoplasmic precursor proteins destined for the mitochondria.

Nonactin is used in urea and ammonium specific electrodes.
产品介绍 Nonactin from Streptomyces Griseus: a mixture of the two homolog macrotetrolide antibiotics: Nonactin, Monactin. The Nonactin is not less than 80%, ballanced by Monactin only. The mixture does not contain Dinactin, Trinactin, Tetranactin. Nonactin batches released since May 2010 are better than 95% Nonactin by NMR; detailed information is available on request
生化机理 Nonactin is a macrotetrolide that forms complexes with alkali cations, such as potassium and sodium. Nonactin has been reported to inhibit the processing of cytoplasmic precursor proteins destined for the mitochondria. Nonactin is a uncoupler of oxidative phosphorylation
别名 铵离子载体;Ammonium Ionophore; Werramycin-A; Polynactin

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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途