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抗生素
甲氨蝶呤 水合物
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| M111239-1g | 133073-73-1 | 询价 |
| M111239-250mg | 133073-73-1 | 询价 |
| M111239-500mg | 133073-73-1 | 询价 |
| M111239-5g | 133073-73-1 | 询价 |
产品介绍
- 分子式 C20H22N8O5·xH2O
- 分子量454.44 (anhydrous basis)
- Beilstein号 70669
- EC号
- MDL号 MFCD00064370
- PubChem编号
属性
| 旋光率 | 21 ° (C=0.1, 1N NaOH) |
| 敏感性 | 对光和湿度敏感 |
| 溶解性 | 易溶于稀碱、酸或碱金属的碳酸盐溶液,微溶于稀盐酸,几乎不溶于水、乙醇、氯仿、乙醚. |
| 存贮条件 | 储存温度 -20°C ;充氩保存 |
| 密度 | 1.5360 |
描述
| 应用 | 叶酸拮抗剂，二羟基叶酸还原酶（dihydrofolate reductase）抑制剂。 |
| 生化机理 | Methotrexate trihydrate is the hydrated form of Methotrexate. Methotrexate is a cell cycle arresting agent with varying effects. Methotrexate has been reported to arrest the cell cycle in late G1/S thus leading to the inhibition of the synthesis of DNA, RNA, thymidylates, and proteins. The main mechanism of action is reported to involve the inhibition of enzymes involved in purine metabolism which leads to the accumulation of adenosine or the suppression of intercellular adhesion molecule expression by T cells. Additionally, this compound has been observed to inhibit DHFR. Methotrexate has also been shown to modulate inflammation by promoting adenosine release or inhibiting transmethylation reactions. Methotrexate was also noted to decrease IL-1 production in adherent splenic cells. Additionally offered as, Methotrexate |
| 别名 | 胺甲喋呤水合物;L-氨甲喋呤 水合物;MTX 水合物;氟安定 水合物;氨甲叶酸 水合物;氨甲喋呤 水合物;对-[(2,4-二氨基喋啶-6)-N-甲基甲氨基]苯甲酰谷氨酸 水合物;N-[4-[[(2,4-二氨基-6-蝶啶)甲基]甲氨基]苯甲酰]-L-谷氨酸水合物(+)-Amethopterin Hydrate;MTX hydrate;Antifolan hydrate;Methylaminopterin hydrate;L-Amethopterin hydrate;4-Amino-10-methylfolic acid hydrate;L-4-Amino-N10-methylpteroylglutamic acid hydrate; |
甲氨蝶呤 水合物信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于甲氨蝶呤 水合物报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途