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梭菌蛋白酶 来源于溶组织梭菌

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产品参数
货号 CAS号 操作
C128677-5mg 9028-00-6 询底价
C128677-1mg 9028-00-6 询底价
产品介绍

属性

存贮条件 储存温度2-8℃

描述

应用 A protease that cleaves proteins on the carboxyl bond of arginine
产品介绍 Clostripain (Endoproteinase-Arg-C) is a two chain proteinase associated with collagenase and isolated from Clostridium histolyticum. It is highly specific for the carboxyl peptide bond of arginine. Clostripain has a sulfhydryl requirement; it is activated by dithiothreitol, cysteine, or other sulfhydryl containing reagents. The presence of calcium ions is essential. The enzyme is inhibited by oxidizing agents and sulfhydryl reactants and by Co2+, Cu2+, Cd2+, and heavy metal ions. Citrate, borate, and Tris anions are less inhibitory.
备注 Chromatographically purified. A dialyzed, lyophilized pre-activated powder.
生化机理 Clostripain from Clostridium histolyticum is composed of two polypeptide chains, with molecular masses of 41.7 kDa and 15.4 kDa. Clostripain has a highly restricted substrate specificity for Arg-Xaa peptide bonds. Therefore, clostripain has been explored as a potential enzyme for protein sequencing purposes. It has also been studied as a catalyst for condensation of pharmaceutically important peptides containing Arg-Pro bonds.
别名 ;Endoproteinase-Arg-C;Clostridiopeptidase B;Proteinase from Clostridium histolyticum

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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途