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酶·辅酶
丁酰胆碱酯酶 来源于马血清
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| B128570-0.5KU | 9001-08-5 | 询底价 |
| B128570-2KU | 9001-08-5 | 询底价 |
产品介绍
- 分子式
- 分子量
- Beilstein号
- EC号 232-579-2
- MDL号 MFCD00081455
- PubChem编号
属性
| 存贮条件 | 储存温度 2-8°C |
描述
| 应用 | Selective inhibition of BChE activity can be used in the detection of organophosphates.Its use in the treatment of organophosphate toxicity has been explored. It has been reported that the level of BChE in human blood correlates to the degree of protection against potentially toxic nerve agents.Cholinesterases have also been investigated for their role in Alzheimer’s disease. |
| 产品介绍 | Butyrl Cholinesterase catalyzes the hydrolysis of a number of choline esters according to the following reaction:Acylcholine + H2O → choline + acid It is a tetrameric glycoprotein with four subunits of equal size, each having a molecular weight of 110 kDa. Butyryl cholinesterase hydrolyzes butyrylcholine four times more rapidly than acetylcholine. Unlike acetyl cholinesterase, it does not hydrolyze D-≥-methyl acetylcholine. It is inhibited by 10-5 M physostigmine, numerous organophosphate esters, the carbamate derivates and quaternary ammonium salts. |
| 备注 | A lyophilized powder. |
| 生化机理 | Butyrylcholinesterase (BChE) is a serine hydrolase that is structurally similar to acetylcholinesterase (AChE), but differs in substrate specificities and inhibitor sensitivities. BChE can, unlike AChE, efficiently hydrolyze larger esters of choline such as butyrylcholine and benzoylcholine. The enzyme is a tetrameric glycoprotein with four equal subunits (110 kDa each). The enzyme is activated by Ca2+ and Mg2+ and the activity is constant over the pH range 6.0-8.0. It is inhibited by Betaine, nicotine, organophosphates, carbamates. |
| 别名 | BChE；拟胆碱酯酶；酰胆碱酰基水解酶;Choline esterase,butyryl;Acylcholine acyl-hydrolase;Pseudocholinesterase;Cholinesterase,Butyryl from Horse Serum |
丁酰胆碱酯酶 来源于马血清信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于丁酰胆碱酯酶 来源于马血清报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途