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酶·辅酶
磷酸二酯酶I 来源于东部菱背响尾蛇毒液
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| P128636-100UN | 9025-82-5 | 询价 |
产品介绍
- 分子式
- 分子量
- Beilstein号
- EC号 232-806-5
- MDL号 MFCD00131883
- PubChem编号
属性
| 存贮条件 | 储存温度 -20°C |
描述
| 应用 | Phosphodiesterase (PDE) is any enzyme that is used to breaks phosphodiester bonds. It is a membrane-bound glycoprotein that is used to catalyze the hydrolysis of various nucleotide polyphosphates. Phosphodiesterase I is used in phosphodiesterase activation assays to hydrolyze AMP. |
| 产品介绍 | Venom exonuclease (Phosphodiesterase I) successively hydrolyzes 5'-mononucleotides from 3'-OH-terminated ribo- and deoxyribo-oligonucleotides. The enzyme has an optimal pH range of 9.8-10.4 and a molecular weight of 115 kDa. Phosphodiesterase is inhibited by reducing agents such as glutathione, cysteine and ascorbic acids. It is completely inhibited by 5mM EDTA while ATP, ADP and AMP are partial inhibitors. The enzyme has an absolute requirement for Mg2+. |
| 备注 | Purified by the method of Williams, Sung and Laskowski, JBC, 236, 1130 (1961). Further treated to inactivate contaminating 5'-nucleotidase activity according to Sulkowski and Laskowski: BBA, 240, 443 (1961). Lyophilized in vials. |
| 生化机理 | Phosphodiesterase I breaks phosphodiester bonds and catalyzes the hydrolysis of various nucleotide polyphosphates. Phosphodiesterase I is released from eucaryotic plasma membranes by phosphatidylinositol-specific phospholipase C. |
| 别名 | 磷酸二酯酶;磷酸二脂酶;磷酸二脂酶I;5′-核酸外切酶;寡核苷酸5′-核苷酸水解酶;5′-Exonuclease;Oligonucleate 5′-nucleotidohydrolase |
磷酸二酯酶I 来源于东部菱背响尾蛇毒液信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于磷酸二酯酶I 来源于东部菱背响尾蛇毒液报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途