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荧光试剂
乙氧基试卤灵
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| R131523-25mg | 5725-91-7 | 询底价 |
| R131523-5mg | 5725-91-7 | 询底价 |
产品介绍
- 分子式 C14H11NO3
- 分子量241.24
- Beilstein号 225973
- MDL号 MFCD00037661
- PubChem编号 24894527
属性
| 溶解性 | Soluble in DMSO (5 mg/mL), ethanol (5 mg/mL), chloroform, dichloromethane, DMF (5 mg/mL), alcohols, and methanol. Insoluble in water. |
| 存贮条件 | 储存温度-20°C |
描述
| 应用 | 7-Ethoxyresorufin (7-ER) is a substrate used in environmental toxicology studies to monitor ethoxyresorufin-O-deethylase catalytic activity in the EROD assay. The EROD assay monitors the induction of the xenobiotic-metabolizing enzyme cytochrome P-450 (CYP) 1A1 and is a widely used biomarker for exposure of wildlife to substances that bind the aryl hydrocarbon (Ah) receptor. It provides evidence of receptor-mediated induction of cytochrome P450-dependant monooxygenases (the CYP1A subfamily specifically) by xenobiotic chemicals. |
| 产品介绍 | 7-Ethoxyresorufin is a fluorimetric substrate and suicide inhibitor of CYP (cytochrome P450). Also shown to inhibit several reductase enzymes, specifically CYPOR (NADPH-P450 reductase). The binding to CYP (cytochrome P450) is thought to inhibit the vasorelaxant response to acetylcholine. 7-Ethoxyresorufin has also demonstrated inhibition of NO synthesis by uncoupling neuronal NOS1 (nitric oxide synthase); it is a noncompetitive inhibitor of neuronal NOS1 with respect to L-arginine with a Ki value of 0.76 +/- 0.06 μM. 7-Ethoxyresorufin is a substate of CYP1A1. |
| 别名 | 7-乙氧基-3H-吩恶嗪-3-酮;7-乙氧基resorufin;7-ER ;Ethoxyresorufin; 7-Ethoxy-3H-phenoxazin-3-one; O7-Ethylresorufin; 7-Ethoxyresorufin; 7-ER; 7-Ethoxy Resorufin |
乙氧基试卤灵信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于乙氧基试卤灵报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途