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7-氨基放线菌素D(7-AAD)

品牌 厂商性质 产地 货期
阿拉丁 生产商 上海 现货

在线咨询 询底价
产品参数
货号 CAS号 操作
A131295-1mg 7240-37-1 询底价
A131295-25mg 7240-37-1 询底价
A131295-5mg 7240-37-1 询底价
产品介绍

  • 分子式 C62H87N13O16
  • 分子量1270.43000
  • Beilstein号
  • EC号
  • MDL号 MFCD00077295
  • PubChem编号

属性

熔点 252-253 °C
敏感性 对光和湿度敏感
溶解性 Soluble in DMSO (20 mg/ml), ethanol, chloroform (1 mg/ml), and dichloromethane (20 mg/ml).
存贮条件 储存温度-20℃

描述

应用 A fluorescent DNA dye for apoptosis and flow cytomtery studies.
产品介绍 7-Aminoactinomycin D ,an analog of the antibiotic actinomycin D ,is a fluorescent DNA dye which is useful for quantifying apoptosis. 7-AAD has also been used in studies on cellular necrosis, chromosome analysis and in cell cycle studies. As a fluorescent DNA dye, 7-AAD is able to intercalate DNA via binding to the GC regions. When used in flow cytometery, 7-AAD can be used to discriminate between live cells as well as early and late apoptosis. Additionally, 7-AAD can also be combined with other staining procedures for analysis of intracellular and cell surface antigens enabling multiparametric analysis. When utilizing 7-AAD with flow cytometery, early and late apoptosis can be studied by varying the concentration of 7-AAD. During apoptosis, the cellular plasma membrane is altered progressively, which allows the cell membrane to become permeable to 7-AAD. 7-AAD staining can also be adapted to include staining with other dyes for intracellular and cell surface antigens. 7-Aminoactinomycin D is an inhibitor of DNA Polymerase and RNA Polymerase
别名 7-AAD; 7-AminoActinomycin D;7-AAD

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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途