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酶抑制剂
Diclofenac
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| D155733-100g | 15307-86-5 | 询价 |
| D155733-1g | 15307-86-5 | 询价 |
| D155733-25G | 15307-86-5 | 询价 |
| D155733-5g | 15307-86-5 | 询价 |
产品介绍
属性
| 熔点 | 158°C |
| 存贮条件 | 储存温度2-8°C |
描述
| 应用 | Diclofenac (双氯芬酸) 是COX抑制剂，对绵羊的COX-1和-2的IC50分别为60和220 nM。 |
| 产品介绍 | Diclofenac is a non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively. Target: COX Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) taken or applied to reduce inflammation and as an analgesic reducing pain in certain conditions. The primary mechanism responsible for its anti-inflammatory, antipyretic, and analgesic action is thought to be inhibition of prostaglandin synthesis by inhibition of cyclooxygenase (COX). It also appears to exhibit bacteriostatic activity by inhibiting bacterial DNA synthesis. Inhibition of COX also decreases prostaglandins in the epithelium of the stomach, making it more sensitive to corrosion by gastric acid. This is also the main side effect of diclofenac. Diclofenac has a low to moderate preference to block the COX2-isoenzyme and is said to have, therefore, a somewhat lower incidence of gastrointestinal complaints than noted with indomethacin and aspirin. |
| 别名 | 双氯芬酸;2-(2,6-二氯苯氨基)苯乙酸;2-[(2,6-二氯苯基)氨基]-苯乙酸;奥尔芬;2-(2,6-Dichloroanilino)phenylacetic Acid |
Diclofenac信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Diclofenac报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途