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酶抑制剂
熊果酸
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 价格（元） | 操作 |
|---|---|---|---|
| U118635-5g | 77-52-1 | 询价 | |
| U118635-1g | 77-52-1 | 询价 | |
| U118635-250mg | 77-52-1 | 询价 | |
| U118635-10g | 77-52-1 | 询价 | |
| U118635-100g | 77-52-1 | 询价 | |
| U118635-25g | 77-52-1 | 询价 | |
| U107243-1g | 77-52-1 | 询价 | |
| U107243-250mg | 77-52-1 | 询价 | |
| U107243-5g | 77-52-1 | 询价 | |
| U107242-20mg | 77-52-1 | 109 | 询价 |
产品介绍
- 分子式 C30H48O3
- 分子量456.70
- Beilstein号 2228563
- EC号 201-034-0
- MDL号 MFCD00009621
- PubChem编号 24889274
属性
| 熔点 | 292 °C |
| 旋光率 | +58.0 to +65.0 deg(C=1, Pyridine) |
| 敏感性 | 对空气敏感 |
| 存贮条件 | 存储温度2-8℃;充氩保存 |
| 密度 | 1.0900 |
描述
| 应用 | An anti-angiogenic and anti-proliferative agent |
| 产品介绍 | 存在于天然植物中的一种三萜类化合物。不溶于水，溶于2%酒精的NaOH，溶于热冰醋酸，中度溶于丙酮，微溶于醇、醚、氯仿和二硫化碳。 |
| 生化机理 | Ursolic Acid, a naturally occurring triterpenoid, has been noted to demonstrate anti-angiogenic and anti-proliferative properties. Mechanistic studies suggest that this compound down-regulates MMP-2 and uPA expression in cells via inhibition of Akt, JNK, mammalian target of Rapamycin phosphorylation, and levels of NFκB protein in the nucleus. Other experiments have shown that Ursolic Acid may improve blood glucose, glucose tolerance, insulin tolerance, glycosylated hemoglobin, and plasma leptin levels in diabetic murine models. Additionally, this agent displays a capacity to induce cell cycle arrest and apoptosis through activation of p53 pathway and Bax protein, as well as down-regulation of Bcl-2. |
| 别名 | 乌苏酸;乌索酸;3-羟基-(3β)-乌索-12-烯-28-酸;3β-Hydroxy-12-ursen-28-ic acid |
熊果酸信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于熊果酸报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途