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1,2-dioleoyl-sn-glycero-3-phosphate (sodium salt)
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| D130369-100mg | 108392-02-5 | 询价 |
| D130369-25mg | 108392-02-5 | 询价 |
| D130369-500mg | 108392-02-5 | 询价 |
产品介绍
- 分子式 C39H72O8PNa
- 分子量722.948
- Beilstein号
- EC号
- MDL号
- PubChem编号 24898361
属性
| 存贮条件 | 储存温度 -20°C |
描述
| 应用 | An activator of multiple PKC isotypes |
| 产品介绍 | Phosphatidic Acid, Dioleoyl has been shown to activate PKC α, ε, or ζ isotypes in the cytosol of COS cells. This compound not only stimulates PKC-ζ-mediated phosphorylation of distinctive substrates, but additionally causes an upward shift in electrophoretic mobility of PKC &zeta. Furthermore, experiments have reported Phosphatidic Acid to be generated by hydrolysis of phosphatidylcholine, via phospholipase D (PLD). Mechanistic studies suggest activation of PLD by insulin and consequential generation of Phosphatidic Acid which then induces Raf-1 translocation to cell membranes. Raf-1 is an essential component to the mitogen-activated protein kinase cascade, and once it has crossed over to the plasma membrane, other factors may activate it through phosphorylation. |
| 别名 | 18:1 PA;1,2-二[顺式-9-十八碳烯酰基]-Sn-甘油-3-磷酸酯钠盐;18:1 PA;1,2-Di(cis-9-octadecenoyl)-sn-glycerol 3-phosphate sodium salt;L-α-Phosphatidic acid, dioleoyl sodium salt |
1,2-dioleoyl-sn-glycero-3-phosphate (sodium salt)信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于1,2-dioleoyl-sn-glycero-3-phosphate (sodium salt)报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途